Diabetes and Heart Disease Share Related Genes

Diabetes and Heart Disease Share Related Genes

Diabetes and heart disease share related gene levels and physiology which could lead to ways of treating both diseases together, scientists have discovered.

It has been shown that both type 2 diabetes and cardiovascular disease have similar risk factors including obesity and hypertension as well as sharing the same genetic make-up which could lead to treating the two diseases together, according to a study published in the American Heart Association journal Circulation: Cardiovascular Genetics.

Researchers analyzed the genetic samples of over 15,000 women using a method known as Genome Wide Association Study (GWAS.) They looked for genetic differences in women who had one or both of the conditions in comparison to healthy women.

The researchers found eight ‘molecular pathways’ that were shared by both diabetes and cardiovascular disease along with genes that compose the networks in which these pathways connect and interact. These pathways included how cells stick within tissues, how cells communicate, and how neurons find their paths to connect with target sites.

Heart Disease (Cardiovascular Disease) can refer to conditions that involve narrowed or blocked blood vessels that can lead to a heart attack, chest pain (angina) or stroke. Other heart conditions, such as those that affect your heart’s muscle, valves or rhythm, also are considered forms of heart disease.

Diabetes refers to a group of diseases that affect how the body uses blood sugar (glucose.) Glucose is vital to your health because it’s an important source of energy for the cells that make up your muscles and tissues. It’s also your brain’s main source of fuel.



Sources: Circulation: Cardiovascular Genetics
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